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Direct imaging reveals individual protein-bound glycans in new detail

Posted in biological

Scanning tunnelling microscopy images of simple glycoconjugates and glycosaminoglycans and their corresponding structures.

Scanning tunnelling microscopy has enabled researchers to directly image important sugar molecules attached to lipids and proteins. The experiments provide a picture at the single-molecule level of the sequences and locations of glycans bound to important biomolecules, offering new insight into the role they play in biology.