Lifeboat Foundation

Excellent opportunity.

Dolomite microfluidic chips are helping researchers from the Biodesign Institute at Arizona State University (ASU) to develop novel enzymes capable of polymerising synthetic nucleotides.

Using these chips, the team has created a droplet-based optical polymerase sorting (DrOPS) technique allowing rapid screening for novel polymerase activities in uniform water-in-oil microcompartments. The team’s leader, Professor John C. Chaput – formerly at ASU and currently at the University of California, Irvine – explained: “The creation of synthetic nucleic acids is of great interest to synthetic biologists but, because they are not found in nature, wild type polymerases struggle to process them. To overcome this issue, we are developing novel polymerases using directed evolution in water-in-oil microcompartments. The DrOPS methodology has significant advantages over traditional methods, which are both labour intensive and impractical to perform on a large scale due to the amount of precious artificial nucleotide reagents required for screening.”

Continue reading “Dolomite Lends a Helping Hand to Synthetic Biology Research” »

Researchers genetically modify piglets to be resistant to an incurable disease plaguing hog farms, Porcine Reproductive Respiratory Syndrome (PRSS). The researchers cut out a specific gene to cure the pigs.

A team of researchers from MIT have developed a new technique on the genome-editing system known as CRISPR, which offers precise manipulation of when and where gene editing occurs.

It’s an add-on for CRISPR.

Researchers have created a new genome editing technique called Target-AID, which induces point mutations instead of cutting DNA

Gene editing technology has fantastic potential, but there are remaining issues and questions over safety and specificity. The major contender is currently CRISPR-Cas9, but this induces a double stranded break in DNA which is a slightly riskier approach — particularly if it cuts in other locations too that you don’t want it to. Research teams across the world are both optimising and customising the CRISPR system; creating more accurate versions or versions that regulate gene expression as opposed to editing it. One such team has now built an add-on to CRISPR, Target-AID.

Continue reading “Safer Gene Editing Without Cleaving DNA” »

From selective breeding to genetic modification, our understanding of biology is now merging with the principles of engineering to bring us synthetic biology.

Written, animated and directed by James Hutson, Bridge8.

Continue reading “Synthetic Biology Explained” »

BrainGate technology is no longer the stuff of science fiction. The science of interfacing human brains and other biological neurons with computers has been developing for well over a decade and now, the progress is amazing. While the human mind is an amazing organ, that surpasses any computer ever made. Many fantasize about improving on natural skills and abilities using technology in the form of some sort of brain implant. That dream is about to become a reality. In some ways, it already has according to the BrainGate website.

“BrainGate Company’s current and planned intellectual property (the technology) is based on technology that can sense, transmit, analyze and apply the language of neurons. BrainGate consists of a sensor that is implanted on the motor cortex of the brain and a device that analyzes brain signals.”

Continue reading “The Cyborgs Are Coming: Mankind Is On The Cusp Of Human Brain Augmentation With BrainGate Technology” »

“Liquid Metals to “Soft-Wire” Elastic Electronics”

A few years ago, some friends shared with me an amazing experiment of theirs involving liquid/ fluid base circuitry. Definitely is amazing; and is going to be amazing in where we are taking this type of technology along with synthetic biology.

The shape-shifting metals behind the T-1000 android assassin in the sci-fi movie Terminator 2 may not remain science fiction for long with the development of self-propelling liquid metals that could lead to the replacement of solid state circuits by elastic electronics.

Continue reading “Liquid Metals to ‘Soft-Wire’ Elastic Electronics” »

#CRISPR can be used to alter the genes of not only one organism, but an entire species, through a method of inheritance known as a gene drive. But what happens if something goes awry?

More insights on human conscientious in relation to its state after we die.

Personally, (this is only my own opinion) I believe much of the human conscientious will remain a mystery even in the living as it relates to the re-creation of the human brain and its thinking and decision making patterns on current technology. Namely because any doctor will tell you that a person’s own decisions (namely emotional decision making/ thinking) can be impacted by a whole multitude of factors beyond logical information such as the brain’s chemical balance, physical illness or even injury, etc. which inherently feeds into conscientious state. In order to try to replicate this model means predominantly development of a machine that is predominantly built with synthetic biology; and even then we will need to evolve this model to finally understand human conscientious more than we do today.

Continue reading “World’s Scientists: ‘Human Consciousness Will Remain a Mystery’” »