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Category: bioengineering – Page 211

How CRISPR gene editing puts scientists in the driver’s seat of evolution

CRISPR can help us end many diseases and guide evolution and is probably one of the most powerful tools we have recently added to our toolkit.

Imagine you could edit a mouse’s genes to be resistant to Lyme Disease. The mouse would breed and evolution would take its course, leading to the extinction of the disease. That’s the vision for scientists developing CRISPR, technology that allows scientists to rewrite the code of life. William Brangham talks to Michael Specter who wrote about CRISPR for The New Yorker.

Synthego bags $41M to grow CRISPR synthetic RNA kit biz

Nice.

Synthetic RNA kit business Synthego has raised $41 million to step up its efforts to make CRISPR gene editing easier and more accurate. The West Coast startup relied heavily on tech VCs for the cash, but also gained validation from having CRISPR pioneer Jennifer Doudna invest in its business.

Redwood City, CA-based Synthego exited stealth in August, four years after it was set up by two former SpaceX computer engineers. In those early years, which were bankrolled by an $8.3 million investment in 2013, Synthego established an automated manufacturing process for guide RNA products that it thinks sets it apart from larger competitors in terms of cost, turnaround time and editing efficiency.

Sythengo has persuaded some big names it is on to something. 8VC, an infrastructure-focused VC that also invested in uBiome, led the round with support from fellow new backers AME Cloud Ventures, Elements Capital, OS Fund, Alexandria Equities and ZhenFund. Existing investors including Peter Thiel’s Founders Fund and Menlo Ventures also contributed to the Series B round.

Gene Editing Can Now Change An Entire Species Forever

In Brief CRISPR has opened up limitless avenues for genetic modification. From disease prevention to invasive species control, Jennifer Kahn discusses the discover, application, and implications of gene drives.

Jennifer Kahn, a science journalist for the New York Times, recently did a TED Talk in which she discussed the discovery, application, and implications of a CRISPR gene drive used to make mosquitoes resistant to malaria and other diseases like chikungunya, and Zika.

Watch the talk in the video below, and learn how geneticists are achieving the (seemingly) impossible:

Real ‘Jurassic World’ Scientist Says We Could Bring Back Dinosaurs As Pets

Paleontologist Jack Horner participates in a “Jurassic World” Q&A at the Natural History Museum.

Here at Popular Science, we can’t wait to see Jurassic World, which opens in theaters nationwide today. I mean, who can resist velociraptor biker gangs:

But we were also curious about the real scientific research that inspired the movie. So we talked with Jack Horner, a noted paleontologist who has consulted on the entire Jurassic Park movie franchise, including Jurassic World.

America’s refusal to embrace gene editing could start the next Cold War

New version of this out: https://www.geneticliteracyproject.org/2017/01/02/americas-r…-cold-war/ #transhumanism #biohacking

Unlike other epic scientific advances…the immediate effect of genetic editing technology is not dangerous. Yet, it stands to be just as divisive to humans as the 70-year proliferation of nuclear weaponry.

The playing field of geopolitics is pretty simple: If China or another country vows to increase its children’s intelligence via genetic editing, and America chooses to remain “au naturel” because they insist that’s how God made them, a conflict species-deep will quickly arise.

This type of idea takes racism and immigration to a whole new level. Will America close off its borders, its jobs, its schools, and its general openness to the world to stay pure, old-fashioned human?

In short, will genetic editing start a new cold war? One that bears much finger pointing and verbal reprimands, including the use of derogatory terms like mutants, cyborgs, and transhumanists.

Genetic researchers discover ‘stop’ button for CRISPR gene editing tool

Researchers have discovered a technique that could block the effects of a powerful gene-editing tool to protect adjacent genes against accidental alteration. The breakthrough could be the beginning of a major step forward for genetic engineering.

Scientists at the University of California (UC) in San Francisco researchers have discovered how to switch off the effects of the CRISPR gene editing system. CRISPR has been a major advance for gene editing, but there are difficulties in limiting its effects on adjacent genes. So far this has militated against its use in research, most obviously, into the human genome.

The Ethics of Synthetic Biology

Nice article raising old concerns and debates on ethics. Synbio like any technology or science can in the wrong hands be used to do anything destructive. Placing standards and laws on such technologies truly does get the law abiding researchers, labs and companies aligned and sadly restricted. However, it does not prevent an ISIS, or the black market, or any other criminal with money from trying to meet an intended goal. So, I do caution folks to at least step back assess and think before imposing a bunch of restrictions and laws on a technology that prevents it from helping those in need v. criminals who never follow ethics or the law.

When artists use synthetic biology, are they playing God, or just playing with cool new toys? Scientists Drew Endy and Christina Agapakis weigh in on the ethics.