Lifeboat Foundation

Today, we have to share some bad news about Organovo and its liver tissue bioprinting program.

While in its early stages, bioprinting of human tissue is an emerging technology that is opening up some exciting possibilities, including the potential to one day 3D print entire human organs. This scientific objective has now grown a little bit closer, with researchers at Carnegie Mellon University reporting a breakthrough that enabled the printing of full-scale heart components that in some cases functioned similarly to the real thing.

Over 4000 patients in the United States alone are waiting for a heart transplant, while millions of others worldwide need hearts but are ineligible for the waitlist. The need for replacement organs is immense, and new approaches are needed to engineer artificial organs that are capable of repairing, supplementing, or replacing long-term organ function.

A team of researchers from Carnegie Mellon University has published a paper in Science that details a new technique allowing anyone to 3D bioprint tissue scaffolds out of collagen, the major structural protein in the human body. This first-of-its-kind method brings the field of tissue engineering one step closer to being able to 3D print a full-sized, adult human heart.

The technique, known as Freeform Reversible Embedding of Suspended Hydrogels (FRESH), has allowed the researchers to overcome many challenges associated with existing 3D bioprinting methods, and to achieve unprecedented resolution and fidelity using soft and living materials.

Continue reading “3D printing the human heart” »

The futuristic gizmo will launch this month.

New LulzBot bioprinting hardware coming 2019 with long term goal of printing real functional tissues.

Kyle Reese: The Terminator’s an infiltration unit, part man, part machine. Underneath, it’s a hyperalloy combat chassis — micro processor-controlled, fully armored. Very tough. But outside, it’s living human tissue — flesh, skin, hair, blood, grown for the cyborgs…

3D bioprinting is the automated fabrication of multicellular tissue via spatially defined deposition of cells. The ability to spatially control deposition in the x, y and z axes allows for creation of tissue-specific patterns or compartments, with in vivo-like architecture that mimics key aspects of native biology.

3D bioprinted tissues exhibit a microenvironment more suited to in vivo-like cellular function in comparison to traditional 2D monoculture (or monolayer co-cultures), as well as maintenance of a more defined architecture than is observed in self-aggregated co-culture models.

Scientists around the world are developing revolutionary means by which to 3D print parts of the human body, from skin to internal organs.