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Category: biotech/medical – Page 2,647

A team of Australian researchers have discovered a new method to fight colon and stomach cancer. Their technique involves inhibiting a protein that cancer cells use to rapidly reproduce.

“Our discovery could potentially offer a new and complementary approach to chemotherapy and immunotherapy as options for treating gastrointestinal cancers,” said professor Matthias Ernst, scientific director at the Olivia Newton-John Cancer Research Institute, in a statement.

Hematopoietic cell kinase (HCK) is an enzyme that helps stem cells become blood cells – hematopoietic cells are the stem cells that all blood cells start as. One type of blood cells that HCK helps to code are macrophages, “big eater” white blood cells whose job is to consume and destroy anything that impedes healthy blood, such as cellular debris, microbes and cancer cells.

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DNA protects itself from damage naturally, and scientists are hoping to gain insight into how the process works. When DNA is bathed in ultraviolet light, it can eject a single proton from a hydrogen atom to rid itself of excess energy, ensuring other chemical bonds remain intact. This protective mechanism is called an excited state proton transfer, and it is the focus of new research by a team of scientists.

The researchers used the Linac Coherent Light Source (LCLS) at the SLAC National Accelerator Laboratory to generate X-ray laser pulses capable of probing the nitrogen molecule — in the simple molecule 2-thiopyridone — for quadrillionths of a second. The short period of time matters because when molecules are exposed to this kind of light they react incredibly quickly. The brightness of the light is equally important, because only very brilliant illumination renders these ultrafast changes visible to the researchers.

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“These re-engineered organisms will change our lives over the coming years, leading to cheaper drugs, ‘green’ means to fuel our cars and targeted therapies for attacking ‘superbugs’ and diseases, such as cancer,” wrote Drs. Ahmad Khalil and James Collins at Boston University, who were not involved in the study.

Our brains are often compared to computers, but in truth, the billions of cells in our bodies may be a better analogy. The squishy sacks of goop may seem a far cry from rigid chips and bundled wires, but cells are experts at taking inputs, running them through a complicated series of logic gates and producing the desired programmed output.

Take beta cells in the pancreas, which manufacture and store insulin. If they detect a large spike in blood sugar, then they release insulin; else they don’t. Each cell adheres to commands like these, allowing us—the organism—to operate normally.

This circuit-like nature of cellular operations is not just a handy metaphor. About 50 years ago, scientists began wondering: what if we could hijack the machinery behind these algorithms and reprogram the cells to do whatever we want?

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Billionaire investor Jim Mellon has joined the push to solve age-related diseases and bring rejuvenation biotechnology to the world.

Billionaire biotechnology investor Jim Mellon has unveiled an investment in an ambitious new venture which seeks to tackle ageing and age-related diseases.

Insilico Medicine is a big data analytics company which says its mission is to ‘extend healthy longevity’.

This is a ‘moonshot’ target in health which has seen investment from a number of ambitious research groups in the last few years.

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New one from Liz.

Full Video ► https://goo.gl/tHvTF5
BioViva ► http://bioviva-science.com

Liz Parrish is the Founder and CEO of BioViva Sciences USA Inc. BioViva is committed to extending healthy lifespans using gene therapy. Liz is known as “the woman who wants to genetically engineer you,” she is a humanitarian, entrepreneur and innovator and a leading voice for genetic cures. As a strong proponent of progress and education for the advancement of gene therapy, she serves as a motivational speaker to the public at large for the life sciences. She is actively involved in international educational media outreach and sits on the board of the International Longevity Alliance (ILA). She is the founder of BioTrove Investments LLC and the BioTrove Podcasts which is committed to offering a meaningful way for people to learn about and fund research in regenerative medicine. She is also the Secretary of the American Longevity Alliance (ALA) a 501©(3) nonprofit trade association that brings together individuals, companies, and organizations who work in advancing the emerging field of cellular & regenerative medicine with the aim to get governments to consider aging a disease.

Parrish received two kinds of injections, which were administered outside the United States: a myostatin inhibitor, which is expected to prevent age-associated muscle loss; and a telomerase gene therapy, which is expected to lengthen telomeres, segments of DNA at the ends of chromosomes whose shortening is associated with aging and degenerative disease.

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