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Category: biotech/medical – Page 37

🌿 International Conference “Anti-Aging: Science and Practice of Healthy Longevity” —

October 21–22, 2025 (Online) 🌿

Dear colleagues and friends.

We are pleased to invite you to the International Scientific Conference “Anti-Aging: Science and Practice of Healthy Longevity”, organized by the Gerontology Section of the Moscow Society of Naturalists (MOIP) at Lomonosov Moscow State University, with the support of the Gerontology Society of the Ural Branch of the Russian Academy of Sciences (URAN).

📅 Dates: October 21–22, 2025 🕛 Time: 12:00–16:00 (Moscow time) đŸ’» Format: Online participation (free of charge) đŸ—Łïž Working language: Russian.

đŸ”č October 21 — “Hypoxic Training (Therapy): Modern Aspects of Healthy Longevity Medicine” đŸ”č October 22 — “Fundamental and Clinical Gerontology as the Basis of Healthy Longevity Medicine”

The conference will feature leading scientists from Russia, Germany, Belarus, Kyrgyzstan and other countries. Topics include: ‱ Hypoxic therapy and adaptive mechanisms; ‱ Geroprotection and the biology of aging; ‱ Epigenetic reprogramming and cellular rejuvenation; ‱ Applied aspects of active and healthy longevity.

🔗 Connection links: ‱ Day 1 (October 21): https://my.mts-link.ru/j/38630705/5798697072

Continue reading “🌿 International Conference “Anti-Aging: Science and Practice of Healthy Longevity” —” | >

Cryosphere Chat ft. Emil Kendziorra — Tales from Biostasis 2025, Our Near Death Experiences

The gang catches up with Emil Kendziorra after the Biostasis 2025 conference at the European Biostasis Foundation. Watch it on YouTube here. Topics covered include:

‱ How to get a Tomorrow Bio ambulance in your hometown.
‱ Tomorrow Bio’s plan to collect brain samples to check ultra-structure preservation in its cryonics patients — and how it will respond to what it finds.
‱ What’s new and what’s next for Tomorrow Bio.
‱ Our near death experiences.

Links:
‱ Cryosphere Discord Server: / discord.
‱ Cryonics Subreddit: / cryonics.

A Tiny Peptide Can Freeze Parkinson’s Proteins Before They Turn Toxic

As Parkinson’s disease progresses, harmful protein clumps build up in the brain, blocking communications between neurons and killing them off – but what if we could prevent these clusters from forming?

Researchers led by a team from the University of Bath in the UK have achieved just that in a basic worm model of Parkinson’s. They engineered a peptide, a small amino acid chain, to essentially keep a protein called alpha-synuclein locked in its healthy shape. This prevented the misfolding that leads to clumps.

The potential treatment checks several important boxes: it’s durable, and it can survive inside cells without causing any toxic side effects.

Leukemia cells evade treatment by reshaping their mitochondria, researchers discover

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients—and found a potential way to overcome that resistance.

Team members identified a protein that lets reshape their energy-producing mitochondria in ways that protect them from venetoclax (brand name, Venclexta), a for acute myeloid leukemia that often loses effectiveness after prolonged use.

Blocking that protein with experimental compounds in mice with human acute myeloid leukemia restored the drug’s effectiveness and prolonged survival.

Lab-grown brains with all major cell types support next-generation therapy research

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown from individual donors’ induced pluripotent stem cells, these models—dubbed Multicellular Integrated Brains (miBrains)—replicate key features and functions of human brain tissue, are readily customizable through gene editing, and can be produced in quantities that support large-scale research.

Although each unit is smaller than a dime, miBrains may be worth a great deal to researchers and drug developers who need more complex living lab models to better understand brain biology and treat diseases.

“The miBrain is the only in vitro system that contains all six major cell types that are present in the human brain,” said Li-Huei Tsai, Picower Professor, director of The Picower Professor of Learning and Memory, and senior author of the study describing miBrains, published in the Proceedings of the National Academy of Sciences.

New antivirals could help prevent cold sores by changing cell structures

A class of antivirals called Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1 (HSV-1), the common infection behind oral herpes, according to new research published in Antiviral Research.

HSV-1 causes sores around the mouth, commonly called cold sores or fever blisters. Most people are infected with HSV-1 in childhood, and between 50% and 90% of people worldwide have HSV-1. After the , HSV-1 remains in the body and can reactivate throughout a person’s life. While HSV-1 infections are usually mild, they can be serious and even deadly for people with suppressed immune systems. Finding new, more effective antivirals for this common illness is essential.

Researchers focused on an enzyme called peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, or Pin1, that regulates protein stability, function, and cellular structure. When this is dysregulated, it can play a role in a variety of conditions, including obesity, cancer, , and more. Viruses, such as cytomegalovirus (CMV) and SARS-CoV-2, are known to affect Pin1, and Pin1 have been developed to reduce the impact of these viruses.

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Clinical resistance is a complex phenomenon in major human cancers involving multifactorial mechanisms, and hypoxia is one of the key components that affect the cellular expression program and lead to therapy resistance. The present study aimed to summarize the role of hypoxia in cancer therapy by regulating the tumor microenvironment (TME) and to highlight the potential of hypoxia-targeted therapy.

Sensor identifies sodium nitrite in drinks using laser-modified cork

A team of researchers from the Federal University of SĂŁo Carlos (UFSCar) in the state of SĂŁo Paulo, Brazil, has developed a sensor that can identify sodium nitrite (NaNO2) in various beverages, including mineral water, orange juice, and wine. This inorganic salt is used as a preservative and fixative to give products such as ham, bacon, and sausages their pink or red color. Depending on the amount, it can cause serious health problems by leading to the formation of nitrosamines, which are carcinogenic compounds.

“This risk motivated us to develop a simple, fast, and accessible way to detect the compound and ensure the quality and safety of liquid consumption,” says Bruno Campos Janegitz, head of the Laboratory of Sensors, Nanomedicine, and Nanostructured Materials (LSNano) at UFSCar. Janegitz coordinated the study, which was published in the journal Microchimica Acta.

“Detection [of NaNO2] in beverages, especially wines, is important for , since its use is not legally permitted in Brazil and most countries,” the authors write in the article.

Transparent wearable monitor gives real-time warnings about overexposure to sunlight

Scientists in South Korea have unveiled a transparent, wearable sensor that monitors a user’s exposure to ultraviolet A (UVA) radiation in real-time. The technology could help prevent sunburn and long-term skin damage that can cause cancer.

Ultraviolet radiation is released naturally by the sun and artificially by tanning beds. The problem with overexposure is that the rays can penetrate deep into the skin and damage DNA, potentially causing cells to grow out of control and leading to cancer. In many countries, the majority of skin cancer cases are linked to this type of overexposure.

While wearing long clothes and hats and applying sunscreen provides valuable protection, the researchers wanted a simple device to alert wearers when exposure reached a certain level. Current sensors often lack the ability to track UVA and are opaque, which makes them uncomfortable and difficult to use in wearable tech like smart glasses.

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