Lifeboat Foundation

Innovation At The Frontiers Of Aesthetic And Regenerative Medicine — Prof. Dr. Alan Widgerow — Division Chief, Center for Tissue Engineering, UCIrvine — Chief Scientific Officer, Galderma.

Prof. Dr. Alan Widgerow, MBBCh, FCS, MMed, FACS, is Division Chief, Research, Center for Tissue Engineering (https://sites.uci.edu/ctelab/team/) and Adjunct Professor Plastic Surgery, Dept of Plastic Surgery, University of California, Irvine (https://faculty.uci.edu/profile/?facu…) and Chief Scientific Officer and Head of Skin Science Center of Innovation at Galderma (https://www.galderma.com/).

Continue reading “Prof. Dr. Alan Widgerow — Division Chief, Center for Tissue Engineering, UC Irvine / CSO, Galderma” »

A newly published study by Sheba Medical Center, Israel’s largest and internationally ranked hospital, shows that AI analysis of medical records as patients are admitted to the ER can accurately identify those at high risk of pulmonary embolism (PE).

A pulmonary embolism is a sudden blockage in an artery in the lung caused by a blood clot, most commonly due to a dislodged clot in the leg. They are normally diagnosed during a CT scan.

Using machine learning, the researchers trained an algorithm to detect a pulmonary embolism before a patient was hospitalized, based on existing medical records.

University of Colorado at Boulder News

In the quest to develop life-like materials to replace and repair human body parts, scientists face a formidable challenge: Real tissues are often both strong and stretchable and vary in shape and size.

A CU Boulder-led team, in collaboration with researchers at the University of Pennsylvania, has taken a critical step toward cracking that code. They’ve developed a new way to 3D print material that is at once elastic enough to withstand a heart’s persistent beating, tough enough to endure the crushing load placed on joints, and easily shapable to fit a patient’s unique defects.

MIT chemists have developed a new way to synthesize complex molecules that were originally isolated from plants and could hold potential as antibiotics, analgesics, or cancer drugs.

In this interview, hosted by Nicolás Cherñavsky, Nir Barzilai and Brad Stanfield discuss metformin, whether or not to use it in non-diabetic patients to slow aging, and the TAME trial.

Nir Barzilai is president of the Academy of Health and Lifespan Research (https://www.ahlresearch.org/), and Brad Stanfield is a primary care physician in Auckland (New Zealand) and runs a YouTube channel (/ @drbradstanfield) with around 250,000 subscribers to explore the latest research and preventive care guidelines.

Continue reading “Metformin and the TAME trial: a conversation with Nir Barzilai and Brad Stanfield” »

In a new study, a molecule identified and synthesized by UCLA Health researchers was shown to restore cognitive functions in mice with symptoms of Alzheimer’s disease by effectively jumpstarting the brain’s memory circuitry.

If proven to have similar effects in humans, the candidate compound would be novel among Alzheimer’s disease treatments in its ability to revitalize memory and cognition, study authors said.

There is really nothing like this on the market or experimentally that has been shown to do this.

Anyone who’s tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer’s disease.

For decades, scientists have focused on how the brain processes information in a hierarchical manner, with different brain areas specialized for different tasks. However, how these areas communicate and integrate information to form a coherent whole has remained a mystery.

Now, researchers at University of California San Diego School of Medicine have brought us closer to solving it by observing how neurons synchronize across the human brain while reading. The findings are published in Nature Human Behavior and are also the basis of a thesis by UC San Diego School of Medicine doctoral candidate Jacob Garrett.

“How the activity of the brain relates to the subjective experience of consciousness is one of the fundamental unanswered questions in modern neuroscience,” said study senior author Eric Halgren, Ph.D., professor in the Departments of Neurosciences and Radiology at UC San Diego School of Medicine.

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Scientists at Stanford University have developed a method for 3D-printing human heart tissue that could eventually be implanted into patients.

Continue reading “3D-Printing Heart Tissue With Human Stem Cells” »