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Category: biotech/medical – Page 78

Polarization photodetectors (pol-PDs) have widespread applications in geological remote sensing, machine vision, and biological medicine. However, commercial pol-PDs usually require bulky and complicated optical components and are difficult to miniaturize and integrate.

Chinese researchers have made important progress in this area by developing an on-chip integrated polarization .

This study, published in Science Advances on Dec. 4, was conducted by Prof. Li Mingzhu’s group from the Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences.

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Three-dimensional (3D) printing isn’t just a way to produce material products quickly. It also offers researchers a way to develop replicas of human tissue that could be used to improve human health, such as building organs for transplantation, studying disease progression and screening new drugs. While researchers have made progress over the years, the field has been hampered by limited existing technologies unable to print tissues with high cell density at scale.

A team of researchers from Penn State have developed a novel bioprinting technique that uses spheroids, which are clusters of cells, to create complex tissue. This new technique improves the precision and scalability of tissue fabrication, producing tissue 10-times faster than existing methods. It further opens the door to developing functional tissues and organs and progress in the field of regenerative medicine, the researchers said.

They published their findings in Nature Communications.

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Fitzgerald says cyborg search and rescue beetles or cockroaches might be able to help in disaster situations by finding and reporting the location of survivors and delivering lifesaving drugs to them before human rescuers can get there.

But first, the Australian researchers must master the ability to direct the movements of the insects, which could take a while. Fitzgerald says that although the work might seem futuristic now, in a few decades, cyborg insects could be saving lives.

He’s not the only roboticist creating robots from living organisms. Academics at the California Institute of Technology (Caltech), for example, are implanting electronic pacemakers into jellyfish to control their swimming speed. They hope the bionic jellies could help collect data about the ocean far below the surface.

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Summary: A new study highlights how brain age models can track healthy infant development and reveal environmental influences. Using MRI data from over 600 term and preterm infants, researchers trained machine learning models to predict brain age and identify gaps between predicted and actual ages.

These brain age gaps can indicate whether an infant’s development is faster or slower than expected, with maternal age emerging as a significant influencing factor. Advanced brain development was linked to better cognitive abilities but poorer emotional regulation, suggesting that following normative developmental trajectories may be ideal.

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New research from the Human Cell Atlas offers insights into cell development, disease mechanisms, and genetic influences, enhancing our understanding of human biology and health.

The Human Cell Atlas (HCA) consortium has made significant progress in its mission to better understand the cells of the human body in health and disease, with a recent publication of a Collection of more than 40 peer-reviewed papers in Nature and other Nature Portfolio journals.

The Collection showcases a range of large-scale datasets, artificial intelligence algorithms, and biomedical discoveries from the HCA that are enhancing our understanding of the human body. The studies reveal insights into how the placenta and skeleton form, changes during brain maturation, new gut and vascular cell states, lung responses to COVID-19, and the effects of genetic variation on disease, among others.

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Physicists are getting closer to controlling single-molecule chemical reactions – could this shape the future of pharmaceutical research?

A groundbreaking study demonstrates control over atomic-level matter through nanotechnology. By leveraging the precision of scanning tunneling microscopy, researchers have shown how competing chemical reaction outcomes can be influenced by manipulating energy levels. This advancement allows for targeted reactions, such as those needed for drug synthesis, while reducing unwanted byproducts.

Controlling matter at the atomic level.

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Inhibiting TLR7, an immune signaling protein, may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer’s disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine. The research is published in the journal Science.

Most in vertebrates are encased in sheaths made largely of myelin, a protein that protects the fibers and greatly enhances the efficiency of their signal conduction. The destruction of myelin sheaths—demyelination—can occur in the context of brain inflammation and can lead to cognitive, movement and other neurological problems. The phenomenon is seen in multiple sclerosis (MS), Alzheimer’s, Parkinson’s and other neurological conditions, as well as in ordinary aging.

Demyelination-linked disorders often show sex differences, and in the study, the researchers looked for underlying mechanisms of demyelination that might help explain these differences. Their experiments in mouse models of Alzheimer’s uncovered TLR7 as a driver of inflammatory demyelination especially in males, but also showed that removing or inhibiting this immune protein can protect against demyelination in both males and females.

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🚀 Q: How will Jared Isaacman’s background influence NASA’s future direction? A: Isaacman’s experience as a business leader, philanthropist, pilot, and astronaut will drive NASA towards a bold era of space economy development, focusing on groundbreaking achievements in space science, technology, and exploration.

🌠 Q: What is Isaacman’s vision for NASA’s mission? A: He aims to pursue a thriving space economy, transforming humanity into a space-faring civilization with breakthroughs in manufacturing, biotechnology, mining, and potentially new energy sources.

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When conventional non-invasive treatments for psychiatric diseases fail, clinicians inevitably have to consider brain surgery. However, brain surgery for psychiatric diseases has long been taboo among the general public due to the infamous history of lobotomy. Thankfully, advancements in brain surgery in recent years are changing the narrative.

Bilateral capsulotomy, more commonly known as , is a form of that has been garnering attention in treating treatment-resistant or refractory (OCD). Patients with refractory OCD experience a debilitating degree of repetitive behaviors and thoughts that they are unable to control, thus downgrading their quality of life.

A group of researchers from South Korea demonstrated that a novel non-invasive bilateral capsulotomy called magnetic resonance-guided focused ultrasound (MRgFUS) capsulotomy is efficacious and safe in treating refractory OCD for up to two years. MRgFUS capsulotomy non-invasively and precisely ablates tissues in the brain region of interest. However, the sustained efficacy of this treatment option was unclear.

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