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Category: computing – Page 319

This is a followup trial result to the first trial that reported 2.5 years of epigenetic age reversal This has interesting reports from the actual patients about how they feel and the changes it made to them. After the first trial I sent an email to see if I could do this but I have IBS which Fahy said would disqualify me.

Dr. Greg Fahy gives an update on the TRIIM-X clinical trial at EARD 2022.

The TRIIM-X clinical trial aims to understand how to create a personalized thymus regeneration regimen. By regenerating the thymus, the researchers hope to be able to prevent or reverse certain aspects of immune system aging.

Continue reading “The Thymus As A Key Target For Aging Intervention — Dr. Greg Fahy — EARD 2022” | >

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Not to mention the potential for cost-savings. If you have been severely sick, you will have felt the unfairness of the high cost of drugs. The latest drugs for cancer, cardiovascular or gastrointestinal diseases, nervous disorders, and rare conditions are so costly that even selling an expensive car won’t cover a year’s supply of them.

The most poignant example is that of cancer drugs, whose approval is by far the most wasteful process of all drug types: The FDA approves less than four percent of cancer drugs, meaning 96 percent of them spend more than a decade being tested in petri dishes, mice, and a small set of patients, before scientists finally realize that they aren’t suitable for human use. Each drug in the four percent that does get approved bears an average price tag of more than a billion dollars, a bill passed down to you, the patient-customer.

Given what is at stake, it is not surprising that a growing number of companies are offering their organs-on-chips to pharma, each with a different technology, patented chip design, or organ. The three oldest companies in this space — Hurel Corporation, Hepregen, and Organovo, founded in 2007 — are all from the United States. InSphero (Switzerland, 2009), TissUse (Germany, 2010), and Mimetas (Netherlands, 2011) were started shortly afterward. Nortis (Seattle, 2012) and Emulate (Boston, 2013, by Don Ingber) followed, and after them half a dozen startup companies are fighting to grow in this exciting cauldron. Thanks to the organs-on-chips pioneered by Grotberg, Huh, and Takayama, the day when most new drugs will be developed and tested directly (and only) using human tissues is fast approaching.

Continue reading “The Organ-on-a-Chip Revolution Is Here” | >

Year 2017 😗

In 2015, researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) developed the first on-chip metamaterial with a refractive index of zero, meaning that the phase of light could be stretched infinitely long. The metamaterial represented a new method to manipulate light and was an important step forward for integrated photonic circuits, which use light rather than electrons to perform a wide variety of functions.

Now, SEAS researchers have pushed that technology further — developing a zero-index waveguide compatible with current silicon photonic technologies. In doing so, the team observed a physical phenomenon that is usually unobservable—a of light.

The research is published in ACS Photonics. The Harvard Office of Technology Development has filed a patent application and is exploring commercialization opportunities.

Continue reading “A zero-index waveguide: Researchers directly observe infinitely long wavelengths for the first time” | >

Year 2012 😗

A Sierpinksi carpet is one of the more famous fractal objects in mathematics. Creating one is an iterative procedure. Start with a square, divide it into nine equal squares and remove the central one. That leaves eight squares around a central square hole. In the next iteration, repeat this process with each of the eight remaining squares and so on (see above). One interesting problem is to find the area of a Sierpinski triangle. Clearly this changes with each iteration. Assuming the original square has area equal to 1, the area after the first iteration is 8/9. After the second iteration, it is (8÷9)^2; after the third it is (8÷9)^3 and so on.

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Year 2019 😁

Semiconducting carbon nanotubes (CNTs) printed into thin films offer high electrical performance, significant mechanical stability, and compatibility with low-temperature processing. Yet, the implementation of low-temperature printed devices, such as CNT thin-film transistors (CNT-TFTs), has been hindered by relatively high process temperature requirements imposed by other device layers—dielectrics and contacts. In this work, we overcome temperature constraints and demonstrate 1D–2D thin-film transistors (1D–2D TFTs) in a low-temperature (maximum exposure ≤80 °C) full print-in-place process (i.e., no substrate removal from printer throughout the entire process) using an aerosol jet printer. Semiconducting 1D CNT channels are used with a 2D hexagonal boron nitride (h-BN) gate dielectric and traces of silver nanowires as the conductive electrodes, all deposited using the same printer.

Read more | >

Year 2009 This is awesome 👌 👏

The title character of Ray Bradbury’s book The Illustrated Man is covered with moving, shifting tattoos. If you look at them, they will tell you a story.

New LED tattoos from the University of Pennsylvania could make the Illustrated Man real (minus the creepy stories, of course). Researchers there are developing silicon-and-silk implantable devices which sit under the skin like a tattoo. Already implanted into mice, these tattoos could carry LEDs, turning your skin into a screen.

The silk substrate onto which the chips are mounted eventually dissolves away inside the body, leaving just the electronics behind. The silicon chips are around the length of a small grain of rice — about 1 millimeter, and just 250 nanometers thick. The sheet of silk will keep them in place, molding to the shape of the skin when saline solution is added.

Continue reading “The Illustrated Man: How LED Tattoos Could Make Your Skin a Screen” | >

This would be great for teleporting objects for shipping across the planet or cosmos eventually. 😀

Scientists have created a “holographic wormhole” inside a quantum computer for the first time.

The pioneering experiment allows researchers to study the ways that theoretical wormholes and quantum physics interact, and could help solve some of the most difficult and perplexing parts of science.

The wormhole is theoretical: researchers did not produce an actual rupture in space and time. But the experimental creation of one inside the quantum computer – which saw a message sent between two simulated blackholes – nonetheless allows scientists to examine how they might work, after almost 100 years of theory.

Continue reading “Physicists create ‘holographic wormhole’ inside quantum computer” | >

Conventional light sources for fiber-optic telecommunications emit many photons at the same time. Photons are particles of light that move as waves. In today €™s telecommunication networks, information is transmitted by modulating the properties of light waves traveling in optical fibers, similar to how radio waves are modulated in AM and FM channels.

In quantum communication, however, information is encoded in the phase of a single photon – the photon €™s position in the wave in which it travels. This makes it possible to connect quantum sensors in a network spanning great distances and to connect quantum computers together.

Researchers recently produced single-photon sources with operating wavelengths compatible with existing fiber communication networks. They did so by placing molybdenum ditelluride semiconductor layers just atoms thick on top of an array of nano-size pillars (Nature Communications, “Site-Controlled Telecom-Wavelength Single-Photon Emitters in Atomically-thin MoTe 2 ”).

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Saturn’s moon Titan is one of the weirdest and most intriguing worlds in our solar system. It is the only place we know of in the universe for sure beyond Earth that has rivers, lakes and larger bodies of liquid, but on Titan these features are filled with flammable hydrocarbons like methane and ethane.

Studying Titan in depth has been difficult due to a thick atmosphere of clouds and haze, but NASA’s James Webb Space Telescope (JWST) is giving scientists their first detailed glimpse of those clouds, and by extension, the weather patterns at work on this unique world.

“We had waited for years to use Webb’s infrared vision to study Titan’s atmosphere,” said JWST Principal Investigator Conor Nixon. “Detecting clouds is exciting because it validates long-held predictions from computer models about Titan’s climate, that clouds would form readily in the mid-northern hemisphere during its late summertime when the surface is warmed by the Sun.”

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