Lifeboat Foundation

This finding “proved” the significance of chromosomal rearrangement, a crucial evolutionary indicator of the emergence of a new species.

Researchers from the Chinese Academy of Sciences (CAS) claim to have found a novel technique for programmable chromosome fusion successfully producing mice with genetic changes “that occur on a million-year evolutionary scale” in the laboratory.

The findings could shed light on how chromosome rearrangements—the tidy packages of organized genes provided in equal numbers by each parent, which align and trade or blend traits to produce offspring—influence evolution, reported Phys.org on Thursday.

Continue reading “Researchers engineer first sustainable chromosome changes in mice” »

Microsoft has shut down more than 1,400 malicious email accounts used by cybercriminals to collect stolen customer passwords via ransomware in the past year. The technology company has presented the second edition of ‘Cyber Signals’, a report that it produces periodically on cyber threats and that shows trends in security and cybercrime. In this issue, it offers insight into the evolution of extortion in cybercrime.

In this analysis, the company highlights that the specialization and consolidation of cybercrime have driven ransomware as a service (RaaS), which has become a dominant business model. RaaS programs, such as Conti or REvil, offer cybercriminals the opportunity to buy access to both ransomware payloads, leaked data and payment infrastructure.

Continue reading “Microsoft shuts down over 1,400 email accounts and 531,000 URLs used by ransomware gang that collected stolen customer credentials” »

Earth’s interior is a far from quiet place. Deep below our surface activities, the planet rumbles with activity, from plate tectonics to convection currents that circulate through the hot magmatic fluids far underneath the crust.

Now scientists studying satellite data of Earth have identified something inside Earth we’ve never seen before: a new type of magnetic wave that sweeps around the surface of our planet’s core, every seven years.

Continue reading “Earth has just started emitting Giant Magnetic Waves from its Core” »

Montana this month gave a City of Billings contractor approval to build homes using 3D-printed walls for new construction in the state. The technology Tim Stark, the contractor, is using comes from Apis Cor, a Florida-based technology company that emphatically states on its website, “We print 3D buildings.”

The first time I encountered Apis Cor was when I wrote about the state of 3D-printed buildings back in 2016. Then Apis Cor was Russia-based and was working with a U.S. company. The website links in my posting back then for both the Russian and U.S. company no longer work. So I am guessing that the Apis Cor of today represents the evolution of both the technology platform as well as the business.

The current version of Apis Cor has constructed a number of pilot homes in the U.S. and the biggest 3D-printed building in the world in the United Arab Emirates. The technology has complied with some international building code standards but not yet in the U.S. Getting regulatory approval from the state of Montana, however, will likely open the door to seeing 3D printers being used more extensively here in North America, and can help lower the cost of home builds and solve growing demand.

Brain cells with the same “birthdate” are more likely to wire together into cooperative signaling circuits that carry out many functions, including the storage of memories, a new study finds.

Led by researchers from NYU Grossman School of Medicine, the new study on the brains of mice developing in the womb found that brain cells (neurons) with the same birthdate showed distinct connectivity and activity throughout the animals’ adult lives, whether they were asleep or awake.

Published online August 22 in Nature Neuroscience, the findings suggest that evolution took advantage of the orderly birth of neurons—by gestational day—to form localized microcircuits in the hippocampus, the brain region that forms memories. Rather than attempting to create each new memory from scratch, the researchers suggest, the brain may exploit the stepwise formation of neuronal layers to establish neural templates, like “Lego pieces,” that match each new experience to an existing template as it is remembered.

The James Webb space telescope continues to dazzle. After releasing the telescope’s first images in July, NASA and the other agencies behind the new telescope have continued to monitor and observe new galaxies and celestial phenomena. Now, the Cosmic Evolution Early Release Science Study (CEERS) has released James Webb’s largest image to date.

The new image is a mosaic that includes multiple pieces of data put together by people working on CEERS. The team is made up of 105 scientists and 19 investigators stationed across 28 institutions in the world. They captured all of the data using the new telescope. Together they all make up James Webb’s largest image to date.

The data was gathered using James Webb’s Near Infrared Camera (NIRCam), its Near Infrared Spectrograph (NIRSpec), and its Mid-Infrared Instrument (MIRI). Each part of the data was taken parallel to the others. Researchers then carefully stitched them together. The instruments capture data using wavelengths that aren’t visible to the naked eye. They then translated the data into visible images.

Somerville and John Gibbons, a genomicist at the University of Massachusetts, Amherst, independently focused on food fermentation, which helped early farmers and herders transform fresh produce and milk into products that can last months or years. Gibbons took a close look at the genome of Aspergillus oryzae, the fungus that jump-starts production of sake from rice and soy sauce and miso from soybeans.

When farmers cultivate A. oryzae, the fungus—a eukaryote, with its DNA enclosed in a nucleus—reproduces on its own. But when humans take a little finished sake and transfer it to a rice mash to begin fermentation anew, they also transfer cells of the fungal strains that evolved and survived best during the first round of fermentation.

Gibbons compared the genomes of scores of A. oryzae strains with those of their wild ancestor, A. flavus. Over time, he found, selection by humans had boosted A. oryzae’s ability to break down starches and to tolerate the alcohol produced by fermentation. “The restructuring of metabolism appears to be a hallmark of domestication in fungi,” he reported last week at Microbe 2022, the annual meeting of the American Society for Microbiology. For example, domesticated Aspergillus strains may have up to five times more copies of a gene for metabolizing starches as their ancestor—“a brilliant way for evolution to turn up this enzyme,” Wolfe says.

A simple statistical test shows that contrary to current practice, the “gaps” within DNA protein and sequence alignments commonly used in evolutionary biology can provide important information about nucleotide and amino acid substitutions over time. The finding could be particularly relevant to those studying distantly related species. The work appears in Proceedings of the National Academy of Sciences.

Biologists studying evolution do so by looking at how DNA and protein sequences change over time. These changes can be sequence length changes—when specific nucleotides are deleted or added at certain positions—or substitutions, where one nucleotide type is exchanged for a different type at a given point.

“Think of the DNA sequence and its evolution as a sentence being copied by different people over time,” says Jeff Thorne, professor of biological sciences and statistics at NC State and a co-corresponding author of the research. “Over time, a letter in a word will change—that’s a substitution. Leaving out or adding letters or words correspond to deletions or insertions.”