Year 2022 Solar powered mitochondria could enable humans to use light to recharge their mitochondria and extend life also their bodies would be recharged by fuel from the sun.
Using light to optogenetically power mitochondria, this study shows that opposing the age-related decline in mitochondrial membrane potential leads to increased healthspan and lifespan in Caenorhabditis elegans. This result points to mitochondrial charge as a fundamental regulator of biological aging.
Single-cell profiling in the human cortex reveals aging-associated transcriptomic changes across all brain cell types, which overlap with effects with Alzheimer’s disease and show a convergent signature with psychopathology across multiple cell types.
While current treatments for ailments related to aging and diseases like type 2 diabetes, Alzheimer’s, and Parkinson’s focus on managing symptoms, Texas A&M researchers have taken a new approach to fight the battle at the source: recharging mitochondrial power through nanotechnology.
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When we need to recharge, we might take a vacation or relax at the spa. But what if we could recharge at the cellular level, fighting against aging and disease with the microscopic building blocks that make up the human body?
When we need to recharge, we might take a vacation or relax at the spa. But what if we could recharge at the cellular level, fighting against aging and disease with the microscopic building blocks that make up the human body?
The ability to recharge cells diminishes as humans age or face diseases. Mitochondria, often called the powerhouse of the cell, are central to energy production. When mitochondrial function declines, it leads to fatigue, tissue degeneration, and accelerated aging. Activities that once required minimal recovery now take far longer, highlighting the role that these organelles play in maintaining vitality and overall health.
While current treatments for ailments related to aging and diseases like type 2 diabetes, Alzheimer’s, and Parkinson’s focus on managing symptoms, Texas A&M researchers have taken a new approach to fight the battle at the source: recharging mitochondrial power through nanotechnology.
The accumulation of mutations in DNA is often mentioned as an explanation for the aging process, but it remains just one hypothesis among many. A team from the University of Geneva (UNIGE), in collaboration with the Inselspital, University Hospital of Bern and the University of Bern (UNIBE), has identified a mechanism that explains why certain organs, such as the liver, age more rapidly than others.
The mechanism reveals that damages to non-coding DNA, which are often hidden, accumulate more in slowly proliferating tissues, such as those of the liver or kidneys. Unlike in organs that regenerate frequently, these damages remain undetected for a long time and prevent cell division. These results, published in the journal Cell, open new avenues for understanding cellular aging and potentially slowing it down.
Our organs and tissues do not all age at the same rate. Aging, marked by an increase in senescent cells —cells that are unable to divide and have lost their functions—affects the liver or kidneys more rapidly than the skin or intestine.
The senior population of Japan aswell as the global population needs to consider taking high dosages of nad plus as it has essentially proven that it can reverse the hallmarks of aging.
Japanese aged 65 or older now account for nearly 30 percent of the population, government data shows.
The Road To Wisdom — Dr. Francis Collins, MD, PhD — Former Director, National Institutes of Health (NIH); Distinguished Investigator, Center for Precision Health Research, National Human Genome Research Institute.
Dr. Francis S. Collins, M.D., Ph.D., (https://www.francisscollins.com/) is the former Director of the U.S. National Institutes of Health (NIH), where as the longest serving director of NIH (spanning 12 years and three presidencies) he oversaw the work of the largest supporter of biomedical research in the world, from basic to clinical research.
Dr. Collins continues to serve as NIH Distinguished Investigator.
Center for Precision Health Research, at the National Human Genome Research Institute (NHGRI — https://irp.nih.gov/pi/francis-collins).
Dr. Collins is a physician-geneticist noted for his landmark discoveries of disease genes and his leadership of the international Human Genome Project, which culminated in April 2003 with the completion of a finished sequence of the human DNA instruction book. He served as director of the National Human Genome Research Institute at the NIH from 1993–2008.
Dr. Collins’ research laboratory has discovered a number of important genes, including those responsible for cystic fibrosis, neurofibromatosis, Huntington’s disease, a familial endocrine cancer syndrome, and most recently, genes for type 2 diabetes, and the gene that causes Hutchinson-Gilford progeria syndrome, a rare condition that causes premature aging.
She’s been doing stem cell therapy for 8 years. She is 53.
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Humans have been trying to cheat death for thousands of years. Myths about elixirs promising immortality span various cultures, as do real concoctions that often did more harm than good. One of the most misguided attempts at creating a potion for immortality involved the first emperor of China and mercury pills. In his obsession with finding a formula that would grant him eternal life, Qin Shi Huang downed mercury and other toxic substances nearly two millennia ago, believing his alchemists had hit upon the perfect magical tonic. Unsurprisingly, he died prematurely at age 49.
Archeologists have discovered another 2,000-year-old “elixir for immortality” that sheds light on the true cost of chasing down eternal life.
While excavating the tomb of a Western Han noble family in China’s Henan province in 2018, researchers unearthed a bronze pot. At first, the team thought the liquid inside was wine, but more recently determined that it was an alchemist’s formulation: a yellow liquid containing potassium nitrate and alunite. These two ingredients are cited in ancient Taoist texts as ingredients for immortality. Potassium nitrate is an inorganic salt used today as a natural source of nitrate, and is a useful ingredient in food preservatives, fertilizer, and fireworks. Alunite is a mineral that forms in volcanic or sedimentary environments when sulfur-rich minerals oxidize. It has historically been used to make alum, which is important for water purification, tanning, and dyeing.
Growing immature eggs from old mice in the ovarian structures of young mice can reverse signs of ageing in the eggs1.
“Think of this as a five-star anti-ageing spa for the old egg,” says Rong Li, a cell biologist at the National University of Singapore (NUS), who co-authored a study describing the results.
When the rejuvenated eggs were fertilized, the resulting embryos were almost four times more likely to give rise to healthy pups than the eggs that matured in the old environment. The results are published in Nature Aging today.
