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Researchers at The University of Texas MD Anderson Cancer Center have shown that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models. If these findings are validated in clinical trials, they could have important therapeutic implications for age-related diseases such as Alzheimer’s, Parkinson’s, heart disease, and cancer.

The study, published in Cell, identified a small molecule compound that restores physiological levels of telomerase reverse transcriptase (TERT), which normally is repressed with the onset of aging. Maintenance of TERT levels in aged lab models reduced cellular senescence and tissue inflammation, spurred new neuron formation with improved memory, and enhanced neuromuscular function, which increased strength and coordination.

The researchers show that TERT functions not only to extend telomeres, but also acts as a transcription factor to affect the expression of many genes directing neurogenesis, learning and memory, cellular senescence, and inflammation.

Will artificial intelligence save us or kill us all? In Japan, AI-driven technology promises better lives for an aging population. But researchers in Silicon Valley are warning of untamable forces being unleashed– and even human extinction.

Will artificial intelligence make life better for humans or lead to our downfall? As developers race toward implementing AI in every aspect of our lives, it is already showing promise in areas like medicine. But what if it is used for nefarious purposes?

In Japan, the inventor and scientist behind the firm Cyberdyne is working to make life better for the sick and elderly. Professor Yoshiyuki Sankai’s robot suits are AI-driven exoskeletons used in rehabilitative medicine to help stroke victims and others learn to walk again. But he doesn’t see the benefits of AI ending there; he predicts a future world where AIs will live in harmony with humans as a new, benevolent species.

Yet in Silicon Valley, the cradle of AI development, there is an unsettling contradiction: a deep uncertainty among many developers about the untamable forces they are unleashing. Gabriel Mukobi is a computer science graduate student at Stanford who is sounding the alarm that AI could push us toward disaster– and even human extinction. He’s at the forefront of a tiny field of researchers swimming against the current to make sure AI is safe and beneficial for everyone.

What are the promises and perils of AI? And who gets to decide how it will be used?

#documentary #dwdocumentary #technology #AI #UsandThem.

Did you know letting crushed garlic sit for 10+ minutes before cooking it helps preserve more of its healthy polyphenols from heat? I learned a bunch of similar tidbits while researching this article on the best longevity foods!


Want to know the best longevity foods that increase lifespan to add to your diet? We pored through hundreds of studies and made a list!

A new material developed by Tohoku University records and stores stress history in structures through a luminescent effect, offering an innovative solution to monitor aging infrastructure without needing power or complex equipment.

Identifying deteriorating infrastructure can be as challenging as fixing it. However, researchers at Tohoku University have made this process easier with the development of an innovative new material.

The material responds to mechanical stimuli by recording stress history through a luminescent effect called an afterglow. This information is stored for a long time, and by applying the material to the surfaces of structures, researchers can observe changes in the afterglow to determine the amount of stress the material has experienced.

This new technology will give doctors a closer look. Introducing Pillbot: a tiny disposable robot that you swallow to let doctors see inside your body. In a live demo on the TED Talk stage, creators Alex Luekbe and Vivek Kumbhari show how this pill-sized device navigates the inside of your stomach with a camera, giving a direct view of the entire organ — without the discomfort of invasive procedures — paving the way for further exploration of the human body. “Inside each and every one of us holds mysteries and wonders that if unlocked, lead to better health, performance and longevity,” says Luebke. Visit the link in bio to watch the full talk.’