Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: life extension – Page 56

Haven’t heard from Bill Andrews in awhile.

BiOptimizers Magnesium Breakthrough 10% with code Modern10 https://bioptimizers.com/modern. This video brought to you by BiOptimizers.
Here we talk with Dr Bill Andrews all about telomeres, why they are on the critical path of aging and finding a way to lengthen them is required in an complete longevity solution.
Some links are affiliate links so we will earn a commission when they are used to purchase products.

If you would like to support our channel please consider joining our patreon / modernhealthspan.
Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US)
Renue By Science 10% discount code MHS: https://tinyurl.com/bdew4bfs.
NMN Powder https://tinyurl.com/syc7rwkh.
DoNotAge 10% discount code MHS https://tinyurl.com/6dbvhv87
NMN https://tinyurl.com/wyzj2f3d CaAKG https://tinyurl.com/2h79stt2
Wellness Extract 10% discount Code MODERNWE Geranylgeraniol Essential http://wellnessextract.com/RICHARDWE Delta Gold Vit E
n1o1 Nitric Oxide 10% discount with code Modern https://tinyurl.com/3esakm4s.
n1o1 Nitric Oxide Lozenges https://tinyurl.com/yh4rrtht.
Age-Defiance Face Cream https://tinyurl.com/4zr959zh.
OmegaQuant 5% discount Code MODERN https://omegaquant.com/shop/
Bulletproof 15% off with coupon code: HEALTHSPAN15: https://tinyurl.com/4npjk5vp.
Inner Fuel Gut support https://bulletproof.fdf2.net/PyDKDM
Omega-3 Krill Oil https://bulletproof.fdf2.net/xkdxmy.
Pendulum Akkermansia pendulumtherapeutics.sjv.io/baoQVg.
Metabolic Daily https://pendulumtherapeutics.sjv.io/N…
Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MODERN
OneSkin 15% Discount: Code MODERN https://tinyurl.com/3t6tevj8 OS-01 Face Topical Supplement https://tinyurl.com/29c8wrr2
Neurohacker Qualia Senolytic https://tinyurl.com/22t9thrn.
TruDiagnostics 12% Discount Code MODERN TruAGE PACE https://trudiagnostic.pxf.io/oqYVMY
☕If you would like to support our channel, we’d love a coffee…thank you! https://www.buymeacoffee.com/mhealthspan.

⏲️Chapters.
00:00 Why telomeres.
07:10 Telomeres and aging.
14:36 Telomerase in stem cells.
20:15 BiOptimizers.
21:44 Telomere shortening.
23:25 Measuring telomere length.
25:30 Biological age.
30:30 Slowing telomere shortening.
39:30 Supplements to help.
41:30 Sierra Science Chemicals \& Gene therapy.
49:30 How is telomerase repressed.
56:10 Liz Parrish \& Gene therapy.
1:01:40 Gene therapy delivery.
1:09:20 Telomerase \& cancer.
1:17:00 Why aging.
1:20:30 Telomeres \& senescence.
1:24:30 More information.

🌐Links in this video.

Continue reading “Lengthening Telomeres To Rewind the Clock of Aging” | >

It is well-established that chronic MSK pain is the key factor for physical disability in the adult population. 19 The World Health Organization (WHO) estimates that 20–33% (over 1.71 billion individuals) of the global population suffers from chronic MSK pain. 20 This type of disorder is characterized by acute or chronic pain in MSK structures, which involve muscles, tendons, ligaments, bones, and nerves. 21 The most common conditions responsible for visits to a physician’s office are OA, rheumatoid arthritis, myofascial pain syndrome (MPS), and low back and neck pain. 22 Less common incidents are generally accompanying with injuries like of tendon sprains, ligament tears, muscle tears, fractures, and similar damage during sports. 20

If left untreated, these conditions progressively increase suffering, disability, and drug consumption, which subsequently diminish an individual’s quality of life. 23 This also translates to a main community health problem due to significant high expenses for health-care systems and insurance for disability. Advanced age may remain the top variable associated with the increased risk of musculoskeletal disorders (MSDs) and MSK pain; however, these conditions may still unfold at any given age for various reasons. Therefore, every individual is at risk of experiencing MSK pain throughout an entire lifetime. 24 Acute pain can become chronic due to numerous factors. The level of intensity, site, and time of noxious stimuli are dictated by the interplay between mechanical, chemical, and thermal receptors and immune cells. 25 Under standard conditions, noxious stimuli and painful sensations gradually decrease with the progression of healing.

Read more | >

Aging senescent cells do not become hypometabolic.

Instead they become HYPERmetabolic, burning energy faster than their younger selves.

This likely steals energy for other useful cellular functions, possibly accounting for their aberrant behaviors.

As we…

The authors offer a new energy-focused perspective on aging by introducing a brain–body model that positions the brain’s response to cytokine signals of hypermetabolism as a mechanistic link between the cellular hallmarks and organismal manifestations of aging.

Read more | >

BIOHACKER Bryan Johnson who’s shelling out millions in his quest for immortality has revealed the exact steps he follows to reverse his hair loss and get rid of greys.

The tech-tycoon, 47, claimed he’s been able to grow a full head of hair despite being “genetically bald” through a mix of supplements, red light therapy and customised hair oil.

At one time, Bryan was best known for founding the payments company Braintree — but nowadays he’s making headlines for his very expensive quest to turn back the clock and become 18 again.

Read more | >

In this episode of the Longevity Optimization Podcast, Dr. DeGray discusses groundbreaking research in aging and longevity, focusing on combination therapies, the hallmarks of aging, and the potential of stem cell and gene therapies. He emphasizes the importance of rejuvenation over merely slowing aging and explores the role of the immune system in health. The conversation also touches on biological age testing, lifestyle factors, and the future of gene therapy in enhancing longevity.

Aubrey de Grey is a British biomedical gerontologist and the founder of the SENS Research Foundation. He is a leading advocate for regenerative medicine, focusing on reversing the effects of aging by repairing cellular damage. Known for his bold vision of life extension, de Grey believes that with advanced therapies, humans could significantly extend their lifespan. He is the co-author of Ending Aging, and his work continues to shape the future of longevity science.

Takeaways.

Combination therapies are crucial for understanding aging.
Rejuvenation may be easier than slowing down aging.
Stem cell therapies hold great promise for the future.
The immune system plays a significant role in aging.
Biological age testing can provide insights into health.
Gene therapy is a promising avenue for longevity research.
Lifestyle factors have limited impact on lifespan extension.
Understanding the hallmarks of aging is essential for interventions.
Preventative maintenance is key to longevity.
The future of aging research is bright with new technologies.

Chapters.

00:00 Introduction to Longevity and Aging Research.

Continue reading “Exploring Aging and Aging Interventions with Aubrey de Grey” | >