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Category: life extension – Page 634

Let’s formulate the task of life extension slightly differently. Something like this…How can we extend sex appeal?

Gyms and beauty salons are in charge of this question now. There is some success, but it’s mostly superficial. Plastic surgery only masks, but doesn’t delay the processes of aging.

Expanding sex appeal is a complex task. Its aspects include both beauty and the activity of the brain. To be sexually attractive we have to be smart and fun. One cannot solve the problem of dementia with makeup.

We have to be in an excellent physical shape to be sexually attractive, but also things should be running smoothly with our hormonal regulation.

The task of extending the period of sex appeal is extremely science-intensive. It is not only the Viagra, but a complex impact on the whole organism. It is obvious that molecular biology is responsible for sex in the modern world.

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Here’s an article on transhumanism in Oregon’s largest paper, The Oregonian: It highlights something I’m trying to create: the impact of a “longevity vote” in the elections to make a difference for the length of people’s lifespans.

Zoltan Istvan is ready to encourage his supporters to vote for either Hillary Clinton or Donald Trump in November — if one of the major-party candidates agrees to put him to work in the White House.

And they’d better take his offer seriously, because he figures he just might be able to tip the election whichever way he wants.

“If we’re getting down to the end, and it’s close, as expected, this could be appealing to a candidate,” Istvan told The Oregonian this week. He believes he could bring a candidate somewhere between 250,000 and a million votes.

If neither Clinton nor Trump takes him up on his proposed deal, he’ll keep those votes for himself. Istvan, a former journalist, is the presidential candidate for the Transhumanist Party, which he created in 2014.

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MMTP Campaign update “Aging is a disease”.

Crowdfunding Campaign: https://www.lifespan.io/campaigns/the-major-mouse-testing-program/

We are testing a combination of compounds which clear out dysfunctional cells in the body, called Senolytics, to see if we can extend maximum lifespan and healthspan in mice. Please subscribe, share, and fund our Lifespan.io campaign today!

MMTP — Major Mouse Testing Program.
http://majormouse.org

Is a project by the International Longevity Alliance.
http://longevityalliance.org

Subscribe: https://www.youtube.com/user/LifespanIO

Continue reading “MMTP — Major Mouse Testing Program — Interview with Daria Khaltourina — ILA” | >

Treatment with sex hormones recovers serious genetic diseases cells, this is the first demonstration that the lengthening of telomeres is possible in humans with the use of a medication,” says the researcher.

Estudo demostrou que há como estimular a enzima telomerase por meio de hormônios sexuais, tanto masculinos quanto femininos.

Por — Editorias: Ciências, Ciências Biológicas, Ciências da Saúde.

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Sea urchins are remarkable organisms. They can quickly regrow damaged spines and feet. Some species also live to extraordinary old ages and—even more remarkably—do so with no signs of poor health, such as a decline in regenerative capacity or an increase in age-related mortality. These ocean Methuselahs even reproduce as if they were still youngsters.

MDI Biological Laboratory Associate Professor James A. Coffman, Ph.D., is studying the of sea urchins in hopes that a deeper understanding of the process of regeneration, which governs the regeneration of aging tissues as well as lost or damaged body parts, will lead to a deeper understanding of the aging process in humans, with whom sea urchins share a close genetic relationship.

In a paper recently published in Aging Cell, a leading journal in the field of aging biology, with Andrea G. Bodnar, Ph.D., of the Bermuda Institute of Ocean Studies, the scientists shed new light on the aging process in sea urchins, raising the prospect that the physical decline that typically accompanies aging is not inevitable.

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I’m excited to see I’m the fourth most searched 3rd party presidential candidate. Thanks for your support of a science, longevity, and technology platform as an alternative to the establishment. If this continues a nonreligious transhumanist could end up #4 or #5 in the final elections, and even get enough votes (maybe a million or more) to push the US election one way or the other if it’s close.

So much about the 2016 presidential election is unprecedented. But perhaps nothing is more unusual than the electorate’s level of dissatisfaction with both major parties’ likely nominees.

An NBC News-SurveyMonkey poll released earlier this week found that, while Democratic front-runner Hillary Clinton maintains her lead in a head-to-head match-up with presumptive Republican nominee Donald Trump, neither candidate is popular with the public at large.

Approximately 60 percent of respondents told pollsters that they either “disliked” or “hated” Clinton, while 63 percent felt the same way about Trump.

Pollster Laura Wronski noted that 23 percent of respondents said they disliked or hated both Trump and Clinton.

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May turn out to be the “fountain-of-youth gene,” say researchers.

An atherosclerotic lesion. Such lesions can rupture and cause heart attacks and strokes. (credit: UVA School of Medicine)

University of Virginia School of Medicine have discovered that a gene called Oct4 — which scientific dogma insists is inactive in adults — actually plays a vital role in preventing ruptured atherosclerotic plaques inside blood vessels, the underlying cause of most heart attacks and strokes.

The researchers found that Oct4 controls the conversion of smooth muscle cells into protective fibrous “caps” inside plaques, making the plaques less likely to rupture. They also discovered that the gene promotes many changes in gene expression that are beneficial in stabilizing the plaques. In addition, the researchers believe it may be possible to develop drugs or other therapeutic agents that target the Oct4 pathway as a way to reduce the incidence of heart attacks or stroke.

Could impact many human diseases, regenerative medicine

The researchers are also currently testing Oct4′s possible role in repairing cellular damage and healing wounds, which would make it useful for regenerative medicine.

Continue reading “Gene helps prevent heart attack, stroke; may also block effects of aging” | >

The visible impacts of depression and stress that can be seen in a person’s face—and contribute to shorter lives—can also be found in alterations in genetic activity, according to newly published research.

In a series of studies involving both C. elegans worms and human cohorts, researchers from the Indiana University School of Medicine and the Scripps Research Institute have identified a series of genes that may modulate the effects of good or bad mood and response to stress on lifespan. In particular, the research pointed to a gene known as ANK3 as playing a key role in affecting . The research was published May 24, 2016 in the Nature Publishing Group journal Molecular Psychiatry, the top ranked journal in the field of psychiatry.

“We were looking for genes that might be at the interface between mood, stress and longevity”, said Alexander B. Niculescu III, M.D., Ph.D., professor of psychiatry and medical neuroscience at the IU School of Medicine. “We have found a series of genes involved in mood disorders and stress disorders which also seem to be involved in longevity.

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Are you an avid supporter of aging research and a keen longevity activist?
The Biogerontology Research Foundation is offering select summer internships for talented individuals. You’d join a passionate and supportive team in researching diagnostic, prognostic, and therapeutic strategies; advising a panel of investors in developing a roadmap to promote longevity science and related technologies across the globe.

The advertised positions are 3 month internships, with the possibility of continuing afterwards. Free accommodation will be provided for in London, alongside a negotiable salary.

The Biogerontology Research Foundation is a UK based think tank dedicated to aging research and accelerating its application worldwide.

Apply to: [email protected]

Are you an avid supporter of aging research and a keen longevity activist?

The Biogerontology Research Foundation is offering select summer internships for talented individuals. You €™d join a passionate and supportive team in researching diagnostic, prognostic, and therapeutic strategies; advising a panel of investors in developing a roadmap to promote longevity science and related technologies across the globe.

Read more