Researchers used supramolecular nanoparticles to repair the brain’s vascular system and reverse Alzheimer’s in mice. Instead of carrying drugs, the nanoparticles themselves triggered natural clearance of amyloid-β proteins. This restored blood-brain barrier function and reversed memory loss. The results point to a revolutionary new path for treating neurodegenerative diseases.
Category: nanotechnology – Page 4
Lignin increases the stability and effectiveness of herbicide nanoparticles, study shows
A recent study has shown that a fraction obtained from lignin, an organic polymer responsible for the rigidity of plant cell walls, was able to improve the performance of nanoparticles with herbicide.
The work is published in the journal ACS Sustainable Chemistry & Engineering and was recently featured on its cover.
The study was conducted by researchers from three research institutions in the state of São Paulo, Brazil: São Paulo State University (UNESP), the State University of Campinas (UNICAMP), and the Federal University of São Carlos (UFSCar).
A faster, more affordable way to produce quantum nanodiamonds holds promise for medicine and industry
An international team of scientists from three continents led by Dr. Petr Cígler of IOCB Prague has developed a method for creating light-emitting quantum centers in nanodiamonds in only a matter of minutes. In just one week, the process can yield as much material as conventional methods would produce in more than forty years.
Moreover, the resulting nanodiamonds show improved optical and quantum properties. The breakthrough brings us one step closer to the industrial production of higher-quality and more affordable quantum nanodiamonds, which have broad applications in research and technology. The article is published in Advanced Functional Materials.
The research team has introduced a new procedure called Pressure and Temperature Qubits (PTQ), which takes only four minutes. Diamond powder is placed in a press that generates extremely high pressure and temperature, reproducing the conditions found deep within Earth’s mantle. Under these conditions, quantum centers are formed inside the nanodiamonds.
Perovskites reveal ultrafast quantum light in new study
Halide perovskites—already a focus of major research into efficient, low-cost solar cells—have been shown to handle light faster than most semiconductors on the market.
A new paper, published in Nature Nanotechnology, reports quantum transients on the scale of ~2 picoseconds at low temperature in bulk formamidinium lead iodide films grown by scalable solution or vapor methods. That ultrafast timescale indicates use in very fast light sources and other photonic components. Crucially, these effects appear in films made by scalable processing rather than specialized growth in lab settings—suggesting a practical and affordable route to explore ultrafast quantum technology.
“Perovskites continue to surprise us,” said Professor Sam Stranks, who led the study. “This discovery shows how their intriguing nanoscale structure gives rise to intrinsic quantum properties that could be harnessed for future photonic technologies.”
Researcher improves century-old equation to predict movement of dangerous air pollutants
A new method developed at the University of Warwick offers the first simple and predictive way to calculate how irregularly shaped nanoparticles—a dangerous class of airborne pollutant—move through the air.
Every day, we breathe in millions of microscopic particles, including soot, dust, pollen, microplastics, viruses, and synthetic nanoparticles. Some are small enough to slip deep into the lungs and even enter the bloodstream, contributing to conditions such as heart disease, stroke, and cancer.
Most of these airborne particles are irregularly shaped. Yet the mathematical models used to predict how these particles behave typically assume they are perfect spheres, simply because the equations are easier to solve. This makes it difficult to monitor or predict the movement of real-world, non-spherical—and often more hazardous—particles.
Iontronic Circuits: Building Intelligence in Brine
Experiments with membranes offer a path toward scalable neuromorphic computing.
Imagine a future in which computers process information not with streams of electrons but with hydrated ions flowing through salt water, a system that mimics how the brain itself computes. This emerging field—known as iontronics, a portmanteau of ions and electronics—is rapidly growing as researchers design neuromorphic computing devices, inspired by animal nervous systems and powered by electrolyte solutions at the nanoscale [1–3]. Since Leon Chua introduced the memory resistor or “memristor” in the 1970s [4], these components have been considered revolutionary building blocks for neuromorphic computing. A memristor’s electrical resistance depends on the current that flowed through it before it was powered off, offering a way to store information. Unlike solid-state memristors, fluidic ones still face challenges in terms of scalability and integration with a circuit.
Imaging technique maps fleeting intermediates in hydrogen electrocatalysis
Electrocatalytic transformations not only require electrical energy—they also need a reliable middleman to spark the desired chemical reaction. Surface metal-hydrogen intermediates can effectively produce value-added chemicals and energy conversion, but, given their low concentration and fleeting lifespan, they are difficult to characterize or study in depth, especially at the nanoscale.
Memristors achieve stable resistance values tied to fundamental constants of nature
Researchers at Forschungszentrum Jülich, together with international collaborators, have demonstrated for the first time that memristors—novel nanoscale switching devices—can provide stable resistance values directly linked to fundamental constants of nature. This paves the way for electrical units such as electrical resistance to be traced back far more simply and directly than it has been possible to date. By contrast, conventional, quantum-based measurement technology is so demanding that it can only be carried out in a few specialized laboratories worldwide.
The paper is published in the journal Nature Nanotechnology.
Since 2019, all base units of the International System of Units (SI)—including the meter, second, and kilogram—have been based on fundamental natural constants. For example, the kilogram, which was once based on the “prototype kilogram,” is now linked to Planck’s constant h. A meter is defined by the speed of light, and a second by the oscillation of the cesium atom.
Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning
I first explored this amazing work back when it was a preprint! Wang et al. herein developed VIPS (volumetric imaging via photochemical sectioning), a way of using UV light to remove layers of expanded tissue-hydrogel, allowing combination of high-resolution lattice-light sheet microscopy with expansion microscopy. Link: [ https://www.science.org/doi/10.1126/science.adr9109]
In my opinion, this technology has enormous future promise for high-throughput connectomics! They will need to improve their labeling density so that higher expansion factors can be used, but this problem is well-studied and I think the issue will likely be solvable with additional resources/effort.
Optical nanoscopy of intact biological specimens has been transformed by recent advancements in hydrogel-based tissue clearing and expansion, enabling the imaging of cellular and subcellular structures with molecular contrast. However, existing high-resolution fluorescence microscopes are physically limited by objective-to-specimen distance, which prevents the study of whole-mount specimens without physical sectioning. To address this challenge, we developed a photochemical strategy for spatially precise sectioning of specimens. By combining serial photochemical sectioning with lattice light-sheet imaging and petabyte-scale computation, we imaged and reconstructed axons and myelin sheaths across entire mouse olfactory bulbs at nanoscale resolution.