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Sepsis is a condition in which the body responds improperly. More specifically, the infection causes the organs in the body to shut down. This is a serious illness which could lead to extremely low blood pressure or septic shock. In this case, permanent damage to the lungs, kidneys, liver, and other organs can occur. Unfortunately, if the damage is extensive enough, it could be fatal. Common symptoms associated with sepsis includes alteration of mental status, shallow breathing, sweating out of context, lightheadedness, chills, and other symptoms associated with infection or fever. Sepsis can lead to septic shock and raises the risk of death. Symptoms of septic shock include inability to stand, sleepiness, and extreme confusion. Interestingly, symptoms can vary between people, and it is important to monitor bodily changes to detect sepsis as early as possible. Bacterial, viral, or fungal infections can lead to sepsis including common infections such as pneumonia, urinary tract infections, and burns, among others. It is critical to see a doctor if you suspect you are not getting better or if your symptoms worsen. Early detection of sepsis can help improve survival rate and prevent permanent organ damage. Treatments include antibiotics, increased fluids, vasopressors to increase blood pressure, and steroids. Although scientists and physicians have worked to understand sepsis and how to treat it, other discoveries are yet to be made.

A recent study in Nature Immunology by Dr. Antoine Roquilly from Nantes University in France, demonstrated that patients that experienced sepsis build strong immune cells that aid in the prevention of tumor development. It was previously unknown how the immune landscape was shaped after a patient recovered from sepsis. Roquilly and his team wanted to understand the relationship between these exposed immune cells and the risk of developing cancer in the future.

Roquilly’s research team first analyzed big datasets that consisted of information from patients who survived sepsis. Researchers were able to determine the risk of cancer prevalence up to 10 years following the discharge from the hospital for sepsis patients. Interestingly, sepsis survivors had lower risk of developing cancer compared to those that did not have sepsis.

Glioblastomas are an extremely aggressive type of brain tumour, which is why the news this week of a vaccine that has shown promise in fighting them is so exciting. And this comes right off the back of the announcement of another trial of the world’s first personalised mRNA vaccine for melanoma, a kind of skin cancer. Ian Sample talks to Prof Alan Melcher of the Institute of Cancer Research about how these vaccines work and whether they could one day be used to target cancer before it is even detectable on scans.

How to listen to podcasts: everything you need to know.

Summary: Researchers explore the intricate mechanisms of memory and debunk common myths about its function. They argue that memory is not a static recording but a dynamic, editable process akin to a Wiki page, and emphasize that forgetting is a normal part of how our brains prioritize information.

Through practical strategies and cognitive psychology research, the book offers methods to enhance memory, from everyday tasks to complex learning processes. The authors also address real-world implications of memory understanding, such as in judicial settings where misconceptions can affect justice.

Have you ever looked back on a moment and wondered if you made the right choice? Professor Robert Sapolsky has, but he believes that there was no actual choice at that moment. Professor Sapolsky has staked out an extreme stance in the field: we are nothing more than the sum of our biology, over which we had no control, and its interactions with the environment, over which we also had no control. Explore what it looks like to reject the notion of free will and how doing so can be liberating rather than paralyzing and despairing.

About the Speaker.
Professor Robert Sapolsky is the John A. and Cynthia Fry Gunn Professor and a professor of biology, of neurology, and of neurosurgery. Over the past thirty years, he has divided his time between the lab, where he studies how stress hormones can damage the brain, and in East Africa, where he studies the impact of chronic stress on the health of baboons.

Sapolsky’s research is featured in the National Geographic documentary \.

Feb. 1, 2024 – A common condition called polycystic ovary syndrome that causes irregular menstrual cycles has been linked to signs of early cognitive decline.

Known as PCOS, the condition may affect more than 1 in 10 women, and is among the most common causes of infertility. In addition to ovulation problems, PCOS can cause excess hair growth on the face and the other parts of the body, as well as abnormal growths on the ovaries. Women with PCOS are at a particularly heightened risk of getting type 2 diabetes, as well as other serious health conditions like heart disease, high blood pressure, cholesterol problems, and sleep apnea, particularly if the women are overweight.

This latest study looked for possible links between PCOS and brain health in women once they were in their late 40s or older.