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One Stage of Sleep Seems Critical For Reducing Risk of Dementia

The risk of getting dementia may go up as you get older if you don’t get enough slow-wave sleep.

A 2023 study found that over-60s are 27 percent more likely to develop dementia if they lose just 1 percent of this deep sleep each year.

Slow-wave sleep is the third stage of a human 90-minute sleep cycle, lasting about 20–40 minutes. It’s the most restful stage, where brain waves and heart rate slow and blood pressure drops.

Zinc-transporting protein contributes to aggressive growth of brain tumor

In a study published in the Proceedings of the National Academy of Sciences (PNAS), the researchers detail their discoveries about why the brain tumor glioblastoma is so aggressive. Their findings center on ZIP4, a protein that transports zinc throughout the body and sets off a cascade of events that drive tumor growth.

About half of all malignant brain tumors are glioblastomas, the deadliest form of brain cancer with a median survival rate of 14 months.

“Surgery for glioblastoma is very challenging, and patients almost always experience a relapse,” said the study’s senior author. “By better understanding why these brain tumors are so aggressive, we hope to open up paths for new treatments.”

Coming to a Brain Near You: A Tiny Computer

Brain-computer interfaces are already letting people with paralysis control computers and communicate their needs, and will soon enable them to manipulate prosthetic limbs without moving a muscle.

The year ahead is pivotal for the companies behind this technology.

Fewer than 100 people to date have had brain-computer interfaces permanently installed. In the next 12 months, that number will more than double, provided the companies with new FDA experimental-use approval meet their goals in clinical trials. Apple this week announced its intention to allow these implants to control iPhones and other products.